Search projects by research theme
Search projects by schools and centres
A selection of current projects in the School is listed here.
We welcome you to discuss other research project ideas with us. To do this:
Domestic students can contact the Graduate Research Coordinator at the School or Centre in which you wish to undertake research.
International students can use our online enquiry form, which helps us match your research interests with a potential supervisor.
- Investigating the role and formation of sub-nuclear bodies in disease
- Sub-nuclear bodies called ‘paraspeckles’ are important in driving cancer progression and in other disease states. This project will dissect the molecular interactions underpinning paraspeckles as a route to development of novel therapies that alter paraspeckle prevalence in diseased cells.
- Steroids and long-term outcomes in the preterm infant
- Our overarching research goal is to understand the impacts of steroid treatment on the long-term outcomes of preterm subjects. Our specific focus is the balance between the impact of postnatal steroids on neurodevelopment and the cardiorespiratory system.
- Stem cell mechanobiology
- This project will enhance our understanding in mechanotransduction (cells transduce biophysical/mechanical signals into biochemical signals from cell membrane to nucleus) to program stem cells and to design biomaterials for stem cell therapy, tissue engineering and regenerative medicine.
- Fixing the ailing heart
- We have identified a link between the entry of calcium into the heart and the supply of energy in the mitochondria. Calcium entry occurs via the L-type calcium channel. One way that the channel can influence energy production is through the movement of cytoskeletal (structural) proteins within the muscle cell. We activate the L-type calcium channel and use this to report mitochondrial function when testing treatments to improve cardiac function.
- Placental vascularity
- An optimal environment in pregnancy is crucial for appropriate fetal development and long term adult health outcomes. This project will use state-of-the-art imaging techniques to understand the pivotal role that the placenta plays in this process. We aim to better comprehend how disturbances in placental vascular development can impact on fetal growth and development. From this we aim to develop therapeutic interventions to enhance placental vascular development in compromised pregnancies.
- Unravelling the social organisation of a primate super-group
- This project is aimed at resolving the social organisation of a primate super-group which has implications for an understanding of human social evolution.
- The Testosterone and Exercise study
- We are investigating the independent and cumulative effects of testosterone administration and combined aerobic and resistance exercise training on cardiovascular health related outcomes in men.
- The Brain Breaks study
- The Brain Breaks study is a randomised control trial funded by the National Health and Medical Research Council (NHMRC). We are investigating the effect of exercise with and without breaks in sitting time on cognitive function (primary outcome) and brain blood flow (secondary outcome), using state-of-the-art transcranial doppler technology, on older and overweight/obese subjects (55–80 years).
- The Preventia study
- The Preventia study will compare the effects of 6 months of land-based walking versus water-based on the health and function of arteries in the brain, and investigate whether one type of exercise is more effective to improve memory and cognition.
- Exercise as medicine: Optimising the interventions to maximise the benefits
- The aim of this project is to investigate the phenomenon of 'responsers' and 'non-responsers' to exercise training. Specifically, this study will test whether the pattern of responsiveness is linked to a trait that has been inherited (genetic) and/or the modality of exercise undertaken.
- Filling the risk factor gap: How does exercise exert its cardiovascular benefits
- Our research goal is to understand the beneficial effects of exercise on vascular function and health, with a specific focus on the role of blood flow and blood pressure.
- A new type of exercise to improve the health of patients with heart failure
- The purpose of this project is to comprehensively investigate the relative effectiveness of eccentric exercise training (ET), a novel training paradigm in patients with heart failure. Our aim is to compare the effects of ET to those of conventional concentric training (CT) in a superiority trial, where both forms of exercise are performed at a matched cardiovascular intensity i.e. an intensity that elicits the same heart rate response.
- Sleeping your way to healthy arteries: Testing the mechanistic links between sleep, exercise and cardiovascular risk
- This project will explore the link between vascular function and sleep.
- The efficacy of pre-employment screening and work hardening programs on the rate of injury and fitness for work
- This research project is novel as there is little information on the efficacy of pre-employment screening data on prediction of injury rates during subsequent employment.
- The built environment and children's physical activity
- This research investigates the influence of the childcare and neighbourhood built environment on the physical activity levels of young children attending childcare.
- The built environment and child development
- The project will examine the influence of the neighbourhood and home physical environment on early child health and development.